For adults with major depressive disorder (MDD)
when used with an antidepressant

References

  1. Depression. Substance Abuse and Mental Health Services Administration (SAMHSA). Updated April 24, 2023. Accessed June 11, 2025. https://www.samhsa.gov/mental-health/what-is-mental-health/conditions/depression
  2. Gaynes BN, Rush AJ, Trivedi MH, Wisniewski SR, Spencer D, Fava M. The STAR*D study: treating depression in the real world. Cleve Clin J Med. 2008;75(1):57–66.
  3. Substance Abuse and Mental Health Services Administration. Key substance use and mental health indicators in the United States: Results from the 2023 National Survey on Drug Use and Health (HHS Publication No. PEP24-07-021, NSDUH Series H.59). Center for Behavioral Health Statistics and Quality, Substance Abuse and Mental Health Services Administration; 2024. Accessed June 11, 2025. https://www.samhsa.gov/data/report/2023-nsduh-annual-national-report
  4. Hasin DS, Sarvet AL, Meyers JL, et al. Epidemiology of adult DSM-5 major depressive disorder and its specifiers in the United States. JAMA Psychiatry. 2018;75(4):336–346. doi:10.1001/jamapsychiatry.2017.4602
  5. Rush AJ, Trivedi MH, Wisniewski SR, et al. Acute and longer‑term outcomes in depressed outpatients requiring one or several treatment steps: a STAR*D report. Am J Psychiatry. 2006;163(11):1905–1917. doi:10.1176/ajp.2006.163.11.1905
  6. American Psychiatric Association. Practice guideline for the treatment of patients with major depressive disorder (third edition); 2010.
  7. CAPLYTA Prescribing Information.
  8. Kao CH. Neurotransmitters and their influence on mental health disorders. Neurosci Psych Open Access. 2024;7(6):284–286. doi:10.47532/npoa.2024.7(6).284‑286
  9. Montano CB, Jackson WC, Vanacore D, Weisler R. Considerations when selecting an antidepressant: a narrative review for primary care providers treating adults with depression. Postgrad Med. 2023;135(5):449–465. doi:10.1080/00325481.2023.2189868
  10. Shankar GS. Serotonin and sexual dysfunction. J Autacoids Horm. 2015;5(1):e129. doi:10.4172/2161‑0479.1000e129
  11. Data on File (REF-02960).