Transcript

Schizophrenia affects about 2.4 million Americans.

It's a serious disease that can make living a normal life a big challenge.

People experience the symptoms of schizophrenia when certain naturally occurring chemicals in the brain go out of balance.

Two of these chemicals are serotonin and dopamine. Scientists think that restoring the right balance of serotonin and dopamine may help treat the symptoms of schizophrenia.

CAPLYTA is a medicine for the treatment of schizophrenia in adults.

CAPLYTA could help treat symptoms of schizophrenia by adjusting serotonin and dopamine levels in the brain.

Like all medications used to treat schizophrenia, exactly how CAPLYTA works is unknown.

Medicines like CAPLYTA can raise the risk of death in elderly people with dementia-related psychosis who have lost touch with reality due to confusion and memory loss. CAPLYTA is not approved for treating people with dementia-related psychosis.

References

  1. CAPLYTA full prescribing information, 2022.
  2. Joyce JN, Shane A, Lexow N, Winokur A, Casanova MF, Kleinman JE. Serotonin uptake sites and serotonin receptors are altered in the limbic system of schizophrenics. Neuropsychopharmacology. 1993;8(4):315-336.
  3. Schizophrenia. National Institutes of Health. https://archives.nih.gov/asites/report/09-09-2019/report.nih.gov/nihfactsheets/ViewFactSheete76f.html?csid=67&key=S#S. Updated June 30, 2018. Accessed May 13, 2022.
  4. Stahl SM. Stahl's Essential Psychopharmacology: Neuroscientific Basis and Practical Applications. 4th ed. New York, NY: Cambridge University Press; 2013.

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