The courage to
keep moving
Brandy, a real CAPLYTA patient living
with bipolar II depression.
Video begins with white background and text in the center of the screen.
(ON SCREEN TEXT)Jamie's Story with Bipolar II Depression
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(ON SCREEN TEXT)The patient and healthcare provider in this video are sharing their individual experiences. They have been compensated for their time. This promotional resource is brought to you by Johnson & Johnson.
(DESCRIPTION)Camera cuts to Jamie outdoors.
(Jamie)I started feeling depression symptoms when I was a young kid. I did feel down a lot. I don't feel I got the support I needed.
(DESCRIPTION)Camera cuts to Jamie speaking directly to camera.
(ON SCREEN TEXT)Jamie Patient Advocate with Bipolar II Depression
(Jamie)It definitely was a hard thing to deal with, especially at a young age when I didn't understand what was going on.
(DESCRIPTION)Footage of Jamie walking outdoors.
(Jamie)Shortly after I got married, my depression symptoms felt as if they were worsening. When it was causing struggles in our marriage, I personally recognized I need to finally get the help I need.
And at that point, I was diagnosed with major depressive disorder. It was quite a good chunk of time of, you know, 11 to 12 years of trying different antidepressants. I honestly felt depression worsening at times.
Then, when I was in my early 30s, my symptoms became severe. I started becoming dysfunctional at work. I didn't want to craft anymore, so I shut off my craft business and I didn't craft for a long time, and it was kind of saddening for me.
At home, my kids were kind of like, "What is going on with you, Mom?" My husband and I would fight more often.
I would feel these urges to randomly do things that I normally wouldn't. It was just this sudden burst of, "I need to go, I have to do this, and I have to go do it now."
I realized my uncontrollable moods were hurting my relationships with my family, so I decided to open up to my healthcare provider.
When I started bringing up my worsening symptoms, she diagnosed me with bipolar II depression. It made sense when I looked back at the symptoms I experienced for most of my life.
One of the first medications she brought up to me was CAPLYTA (lumateperone).
(DESCRIPTION)Camera cuts to Amy speaking directly to camera.
(ON SCREEN TEXT)Amy Belnap
APRN, PMHNP-BC
(Amy)CAPLYTA is an FDA-approved prescription medication used to treat depressive episodes associated with bipolar I or bipolar II disorder in adults.
CAPLYTA is proven to reduce depressive symptoms from bipolar I and II, and it has a well-established safety profile. It's also one of a few medications approved to treat bipolar II depression, which is what Jamie has.
Bipolar I and II have a similar patient population size, yet many people don't know the difference between them.
In Jamie's case, having bipolar II depression means she tends to experience longer depressive episodes that can be more severe than with bipolar I, while not experiencing debilitating bouts of mania or needing to go to the hospital.
(DESCRIPTION)Footage of Jamie crafting appears with lower-third text.
(ON SCREEN TEXT)3 in 4 patients with bipolar disorder are misdiagnosed, most often with major depressive disorder (MDD).
(Amy)This can make bipolar II hard to diagnose, as it can frequently be confused with major depressive disorder. Antidepressant medications may worsen bipolar symptoms, so a proper diagnosis is critical.
The ability to differentiate bipolar I and bipolar II disorder really hinges on the identification of manic and hypomanic symptoms.
(DESCRIPTION)Lower-third safety text appears on screen.
(ON SCREEN TEXT)High cholesterol and weight gain may occur, as can high blood sugar, which may be fatal. Monitoring is recommended.
(Amy)I've found that most of my patients who take CAPLYTA tolerate it well. Many of them are worried about side effects.
I let them know that in CAPLYTA clinical trials, weight gain and movement disorders were not common. And the dosing is convenient. It's one pill, taken just once a day with or without food.
I thought CAPLYTA could really help Jamie find relief from her symptoms. Of course, every patient's experience with CAPLYTA will be different.
(DESCRIPTION)Pop-up text appears on screen.
(ON SCREEN TEXT)Keep watching to hear more of Jamie's story
(ON SCREEN TEXT)Please see Important Safety Information at the end of this video.
(Amy)I make sure they review the Important Safety Information for CAPLYTA, which is included at the end of this video.
(DESCRIPTION)Lower-third safety text appears on screen.
(ON SCREEN TEXT)Elderly dementia patients have increased risk of death or stroke. CAPLYTA is not approved for dementia-related psychosis.
(VO)Elderly dementia patients have increased risk of death or stroke. CAPLYTA is not approved for dementia-related psychosis.
(DESCRIPTION)Footage of Jamie with her children in the kitchen.
(ON SCREEN TEXT)Call your doctor about new or sudden mood changes, behaviors, or suicidal thoughts right away. Antidepressants may increase these risks.
(VO)Call your doctor about new or sudden mood changes, behaviors, or suicidal thoughts right away. Antidepressants may increase these risks.
(ON SCREEN TEXT)Report fever, confusion, stiff muscles, which may be life-threatening, or uncontrolled muscle movements, which may be permanent.
(VO)Report fever, confusion, stiff muscles, which may be life-threatening, or uncontrolled muscle movements, which may be permanent.
(ON SCREEN TEXT)High cholesterol and weight gain may occur, as can high blood sugar, which may be fatal. Monitoring is recommended.
(VO)High cholesterol and weight gain may occur, as can high blood sugar, which may be fatal.
(ON SCREEN TEXT)Common side effects are sleepiness, dizziness, nausea, dry mouth, feeling tired, and diarrhea. These aren't all the side effects.
(VO)Common side effects are sleepiness, dizziness, nausea, dry mouth, feeling tired, and diarrhea. These aren't all the side effects.
(Jamie)Amy and I had a really good conversation about CAPLYTA. I also liked how there was no titration needed. I was on the effective dose from the start.
(Amy)I let my patients know they may see relief over the course of six weeks. But again, everyone's experience might be different.
(Jamie)Before I started CAPLYTA, I told my healthcare provider about all the medical conditions I had and medications I was taking.
(DESCRIPTION)Lower-third text appears on screen.
(ON SCREEN TEXT)Individual results may vary. Talk to your doctor to see if CAPLYTA might be right for you.
(Jamie)After taking CAPLYTA for a few weeks, I noticed some improvements in my bipolar depression symptoms.
(Amy)I'm happy with the progress Jamie is making on CAPLYTA. It's made such a difference in her bipolar depression symptoms.
I'm glad Jamie trusted me and opened up to me about her challenges with bipolar II. That's what has helped get to the correct diagnosis, and a treatment plan that she's on now.
(Jamie)I'm happy with the progress I've made on CAPLYTA. I still see Amy regularly and I still seek therapy on a routine basis.
It's a relief to know what was causing my symptoms for most of my life. Having relief from my bipolar depression means I am able to focus on other parts of my life, like my work. I love spending time with my family.
To anybody out there who is currently seeking help, go talk to somebody, because it's so worth getting the help you need.
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© Johnson & Johnson and its affiliates 2026
CAPLYTA and LET IN THE LYTE are trademarks of Johnson & Johnson and its affiliates.
Third party trademarks listed are the property of their respective owners. 03/26 US-CAP-2500875

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